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3D Bioprinting in Therapeutics

3D Bioprinting has been increasingly used in areas like Tissue engineering and biomaterials. This technique is also explored in the prevention and therapy of diseases. To speed up the process of drug discovery and development, the conventional process pipeline can be altered by introducing invitro models for testing or even developing drug delivery systems. 3D Bioprinted drugs have been established by depositing therapeutic molecules as oral tablets or in implantable forms.

Among several translational and therapeutic research, The Department of Pharmacy at BITS Pilani Hyderabad strive to work on developing treatment methods for hormonal therapy using the CELLINK’s BIOX pneumatic system.

Some of their post-printing processes include Mechanical strength testing for durability, drug release testing, swelling and porosity to check for the materials properties.

“As we come from a pharmacy background, we initially assumed learning to operate a bioprinter would be daunting but to our surprise CELLINKs user interface and ease of operation helped us pick pace instantly.”

Their team of pharmaceutical researchers focus on the development of drug loaded polymeric films for long-acting drug delivery and cell seeded scaffolds for point of care therapeutic approach as their initial area of application. Pharmaceutical researchers aim to print personalized dosage forms with better ease of operation and lower cost of production. Working towards these applications bring up challenges like stabilizing the material and optimizing print parameters, which create a greater scope of research and development in bioprinting in therapeutics.

Publication Date : February, 2023

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